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Our research interests focus on optically and microscopically tailoring the properties of soft and hard condensed matter materials using Raman microscopy, infrared absorption spectroscopy, atomic force microscopy, and scanning near-field optical microscopy. Such studies, of both fundamental and applied interest, provide important insights for procedure optimization in fabricating new materials important to emerging technological applications, from nanoelectronics and nanophotonics, to medical diagnostics. The students trained in this laboratory not only used advanced technology for successful completion of many degree programs (6 Ph.D. and 12 M.S. from 2007 to present), but also acquired skills leading to future employment.

Research Group

Dr. Felicia S. Manciu, Professor
M.S. Students: Jose Guerrero

Current Projects

• Exploring ways of improving the characteristics of doped diamond electrodes for detection of neurotransmitters in the brain through the neurosurgical technique of Deep Brain Stimulation (DBS)
• Label-free optical monitoring of changes that occur in cancerous specimens and real-time optical detection of neurotransmitters
• Gaining new insights into developing reliable metal oxide materials and transition metal chalcogenide alloys

Publications

1. F. S. Manciu, Y. Oh, A. Barath, A. E. Rusheen, A. Z. Kouzani, D. Hodges, J. Guerrero, J. Tomshine, K. H. Lee, K. E. Bennet. Analysis of Carbon-based Microelectrodes for Neurochemical Sensing. Materials, 12(19), 3186–3199, PMID: 31569398 (2019).
2. F. S. Manciu, M. Manciu, J. D. Ciubuc, E. M. Sundin, K. Ochoa, M. Eastman, W. G. Durrer, J. Guerrero, B. Lopez, M. Subedi, K. E. Bennet. Simultaneous Detection of Dopamine and Serotonin – a Comparative Experimental and Theoretical Study of Neurotransmitter Interactions. Biosensors, 9(1), 3, PMID: 30587770, PMCID: PMC6468865 (2019).
3. J. D. Ciubuc, M. Manciu, A. Maran, M. J. Yaszemski, E. M. Sundin, K. E. Bennet, F. S. Manciu. Raman Spectroscopic and Microscopic Analysis for Monitoring Renal Osteodystrophy Signatures. Biosensors, 8, 38–49, PMID: 29642494, PMCID: PMC6022865 (2018).
4. F. S. Manciu, J. D. Ciubuc, K. Parra, M. Manciu, P. Valenzuela, E. M. Sundin, L. Reza, G. Francia. Label‑free Raman imaging to monitor breast tumor signatures. Technology in Cancer Research & Treatment, 16(4), 461–469, PMID: (2017).
5. K. E. Bennet, J. R. Tomshine, H.-K. Min, F. S. Manciu, M. P. Marsh, S. B. Paek, M. L. Settell, E. N. Nicolai, C. D. Blaha, A. Z. Kouzani, S.-Y. Chang, K. H. Lee. A Diamond-Based Electrode for Detection of Neurochemicals in the Human Brain. Frontiers in Human Neuroscience, 10(102), 1-12, DOI:, PMID:, PMCID: (2016).